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Nicole Draper Selected Research

galactose-6-phosphate dehydrogenase

3/2006Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation.
6/2005Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
10/200411beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
8/2003Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.

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Nicole Draper Research Topics

Disease

5Cortisone reductase deficiency
07/2006 - 08/2003
2Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
07/2006 - 08/2003
2Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2006 - 10/2004
2Obesity
08/2005 - 10/2004
2Pituitary ACTH Hypersecretion
08/2005 - 01/2002
2Glaucoma
08/2005 - 10/2004
2Hypertension (High Blood Pressure)
08/2005 - 08/2003
2Osteoporosis
08/2005 - 10/2004
2Disorders of Sex Development (Intersexuality)
11/2004 - 06/2004
2Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
11/2004 - 06/2004
1Neoplasms (Cancer)
12/2008
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
12/2008
1Insulin Resistance
08/2005
1Feminization
11/2004
1Virilism (Virilization)
11/2004
1Congenital Abnormalities (Deformity)
11/2004
1Alkalosis
08/2003
1Hirsutism
01/2002
1Muscular Diseases (Myopathy)
01/2002
1Cushing Syndrome
01/2002

Drug/Important Bio-Agent (IBA)

511-beta-Hydroxysteroid Dehydrogenase Type 1IBA
03/2006 - 01/2002
4CortisoneFDA Link
07/2006 - 01/2002
4galactose-6-phosphate dehydrogenaseIBA
03/2006 - 08/2003
4EnzymesIBA
08/2005 - 01/2002
3Hydrocortisone (Cortisol)FDA LinkGeneric
08/2005 - 01/2002
3GlucocorticoidsIBA
08/2005 - 01/2002
3Oxidoreductases (Dehydrogenase)IBA
11/2004 - 06/2004
211-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
08/2005 - 08/2003
2MineralocorticoidsIBA
08/2005 - 08/2003
2AndrogensIBA
06/2004 - 08/2003
2Adrenocorticotropic Hormone (ACTH)FDA Link
08/2003 - 01/2002
1Cyclin D3IBA
12/2008
1Proteins (Proteins, Gene)FDA Link
12/2008
1Retinoblastoma ProteinIBA
12/2008
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
12/2008
1Cyclin D1IBA
12/2008
1IsoenzymesIBA
08/2005
117-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA
11/2004
1NADP (NADPH)IBA
10/2004
1Steroid 21-Hydroxylase (21 Hydroxylase)IBA
06/2004
1SteroidsIBA
06/2004
1methylamphotericin B (AME)IBA
08/2003
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2002
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2002